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    | EN

    安適?:鹽酸曲唑酮片

    安適?:鹽酸曲唑酮片

    適應癥:

    適用于抑郁癥的治療,對伴有或不伴有焦慮的患者均有效。

    曲唑酮能阻斷5-HT的再攝取,同時其代謝產物氯芬哌嗪又具有拮抗5-HT的作用,從而產生抗抑郁、抗焦慮的作用;另一方面還能選擇性阻斷H1受體和腎上腺素α受體,尤其是突觸前α2受體,產生明顯的鎮靜和催眠作用。

    研究顯示小劑量曲唑酮能夠減少覺醒次數、縮短入睡潛伏期、增加總睡眠時間,在保持正常睡眠結構的同時還可增加深睡眠,從而提高睡眠質量,具有誘導維持深睡眠,抗焦慮和改善性功能障礙作用。此外,曲唑酮還可以修復SSRIs類藥導致的睡眠紊亂,經常作為SSRIs的輔助治療。

    獲《中國成人失眠診斷與治療指南》推薦


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